The part 1 research included 35 healthy women. Those that got injections of two attainable vaccines developed antibodies to the chlamydia micro organism, however much more testing is required earlier than the vaccine could be prepared for the general public, the researchers added.
“An efficient vaccine in opposition to chlamydia would have huge public well being and financial affect,” mentioned lead researcher Frank Follmann. He’s director of infectious illness immunology on the Heart for Vaccine Analysis at Statens Serum Institute in Copenhagen, Denmark.
“This can be a promising first step on the highway to develop a vaccine,” he mentioned. “The success of the HPV [human papillomavirus] vaccine has proven us how efficient vaccination might be in opposition to a sexually transmitted an infection. We hope to do the identical with chlamydia and, in the long run, mix the 2 vaccines.”
The outcomes of this research are encouraging, and bigger trials are deliberate, Follmann mentioned. “The aim is to vaccinate ladies [and potentially boys] earlier than they change into sexually lively,” he defined.
One knowledgeable mentioned the findings present promise.
“Growing a vaccine in opposition to chlamydia has been difficult,” mentioned Fred Wyand, a spokesman for the American Sexual Well being Affiliation. “The research provides purpose to be hopeful that vaccination to forestall chlamydia will sometime be attainable, however that aim lies sooner or later.”
Within the meantime, Wyand added, “it is necessary to remember that chlamydia is well identified, handled and cured. Because of this it is so necessary to check, and specialists just like the CDC advocate annual chlamydia testing for all sexually lively girls age 25 and underneath.”
Within the vaccine trial, the ladies have been randomly assigned to one among two totally different vaccines or a placebo.
All the girls who obtained the vaccine produced antibodies to chlamydia, however one of many vaccines, referred to as CTH522:CAF01, produced almost six instances extra antibodies than the opposite vaccine, the investigators discovered.
That is the components the researchers suppose ought to be pursued. From these outcomes, nonetheless, it is not a certainty that the vaccine will shield somebody from chlamydia or if the safety will final over the long run, the researchers famous.